Vancomycin as a risk factor for anaphylactoid reaction (Red Man Syndrome): Literature review

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Red man syndrome adverse reaction following intravenous infusion of cefepime.

We report the first case of cefepime-induced "red-man syndrome," which appeared 30 min following drug infusion and was confirmed with a rechallenge test. This syndrome is classically associated with vancomycin infusion and is the result of non-IgE mediated mast cell degranulation. While this adverse effect can be easily managed with drug withdrawal and antihistamine administration, it is unknow...

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Red man syndrome

Vancomycin can cause two types of hypersensitivity reactions, the red man syndrome and anaphylaxis. Red man syndrome has often been associated with rapid infusion of the first dose of the drug and was initially attributed to impurities found in vancomycin preparations. Even after improvement in vancomycin’s purity, however, reports of the syndrome persist. Other antibiotics (e.g. ciprofloxacin,...

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An elderly woman with 'Red Man Syndrome' in association with oral vancomycin therapy: a case report

INTRODUCTION 'Red Man Syndrome' is a recognized adverse reaction to intravenous vancomycin therapy. This case concerns an elderly woman who developed a 'Red Man Syndrome' reaction whilst on oral vancomycin therapy for Clostridium difficile (C difficile) diarrhoea. Isolated case reports exist recording this reaction in association with oral vancomycin therapy in patients with inflammatory bowel ...

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ژورنال

عنوان ژورنال: African Journal of Pharmacy and Pharmacology

سال: 2013

ISSN: 1996-0816

DOI: 10.5897/ajpp2013.3412